Ghassan Daghlas, who monitors settler activity in the northern West Bank, said that settlers blocked a main road that links the West Bank town of Huwwara to Tulkarem and Qalqiliya.
Settlers prevented Palestinian vehicles from passing through, causing a large traffic jam. Around 12 settlers also attacked the village of Urif in Nablus, clashing with local villagers.
Witnesses said the Israeli army was present during the incident but fired tear gas at the villagers.
In 2011, the UN Office for the Coordination of Humanitarian Affairs reported that settler attacks had increased by 50 percent on the previous year.
The Nablus district experienced the majority of settler violence in 2011.