The Friday attack took place near Ras Kamboni town in the Badhaadhe district of Lower Juba region near the border with Kenya, a Press TV correspondent reported.
In a similar incident late on Thursday, a US done attack killed 22 in Kudhaa Island in southern Somalia near the border with Kenya.
Somalia is the sixth country where the US military has conducted drone strikes.
The US has deployed bombing and intelligence drones in Afghanistan, Pakistan, Libya, Iraq and Yemen to launch aerial missile attacks.
Washington claims the airstrikes target militants, though most such attacks have resulted in civilian casualties.
Somalia has been without a functioning government since 1991, when warlords overthrew former dictator Mohamed Siad Barre.
(www.presstv.ir / 21.10.2011)